Upcoming Clinical Trials

  • DRCR AL

Pathology: Radiation Retinopathy

Description: A Randomized Clinical Trial Evaluating Anti-VEGF vs Sustained-Release Corticosteroid vs Observation for Prevention of Visual Acuity Loss due to Radiation Retinopathy.

Study Objectives: This randomized trial will evaluate the effect of intravitreal anti-VEGF or sustained-release corticosteroid compared with observation (sham injections) on long-term visual acuity following treatment of choroidal melanoma with iodine-125 plaque brachytherapy.

Principal Investigator: Dr. Smith

Status: Enrollment by Q1 2023

  • DRCR AN

Pathology: Diabetic Macular Edema (DME)

Description: A Phase 2 Study Evaluating Short-Term Efficacy of Tonabersat (Xiflam) for Diabetic Macular Edema (DME).

Study Objectives: This randomized clinical trial will evaluate the effect of tonabersat (Xiflam) compared with placebo on central subfield thickness (CST) in eyes with center-involved DME and good visual acuity.

Principal Investigator: Dr. Papakostas

Status: Enrollment by Q1 2023

  • DRCR AO

Pathology: Wet Age-Related Macular Degeneration (AMD)

Description: Home OCT-Guided Treatment versus Treat and Extend for the Management of Neovascular AMD.

Study Objectives: Determine if visual acuity outcomes at 2 years in eyes that receive anti-VEGF using Home OCT-guided treatment are non-inferior to those that receive treat and extend (T&E) dosing for nAMD.

Principal Investigator: Dr. Blinder

Status: Enrollment by Q1 2023